PMID- 21171956
OWN - NLM
STAT- MEDLINE
DA  - 20101221
DCOM- 20110324
LR  - 20130703
IS  - 2212-4012 (Electronic)
IS  - 1872-2083 (Linking)
VI  - 4
IP  - 3
DP  - 2010 Nov
TI  - Developments in high-yield system expressed vaccines and immunotherapy.
PG  - 189-97
AB  - Conventional vaccine production techniques are outdated, leaving the world
      defenseless to viruses and pathogens. Successful protection necessitates the
      innovation of strategies that can generate an induced defensive humoral and
      cellular response with: ease of mass production, nominal side-effects, and
      controlled design specificity, all while being cost effective. Fortunately,
      technology exists to facilitate such advances in this billion dollar industry and
      this review is focused on recent publications and patents which hold promise to
      revolutionize the fight against pathogenic illnesses.
AD  - Biomedical Engineering Program, College of Engineering, University of Arkansas,
      203 Engineering Hall, Fayetteville, AR 72701, USA.
FAU - Geels, Marissa
AU  - Geels M
FAU - Ye, Kaiming
AU  - Ye K
LA  - eng
GR  - R01 AI078357/AI/NIAID NIH HHS/United States
GR  - R01 AI078357-01A2/AI/NIAID NIH HHS/United States
GR  - R01 AI078357-03/AI/NIAID NIH HHS/United States
PT  - Journal Article
PT  - Review
PL  - United Arab Emirates
TA  - Recent Pat Biotechnol
JT  - Recent patents on biotechnology
JID - 101309942
RN  - 0 (Bacterial Vaccines)
RN  - 0 (DNA, Recombinant)
RN  - 0 (Influenza Vaccines)
RN  - 0 (Membrane Proteins)
RN  - 0 (Recombinant Proteins)
RN  - 0 (Vaccines)
RN  - 0 (Vaccines, DNA)
RN  - 0 (Vaccines, Synthetic)
SB  - IM
MH  - Bacterial Vaccines/biosynthesis
MH  - Cost-Benefit Analysis
MH  - DNA, Recombinant/genetics
MH  - Drug Industry
MH  - Genetic Vectors
MH  - Humans
MH  - *Immunotherapy
MH  - Influenza Vaccines/*biosynthesis
MH  - Membrane Proteins/metabolism
MH  - Patents as Topic
MH  - *Reassortant Viruses
MH  - Recombinant Proteins/metabolism
MH  - Vaccines/*biosynthesis
MH  - Vaccines, DNA/biosynthesis
MH  - Vaccines, Synthetic
PMC - PMC3020102
MID - NIHMS238776
OID - NLM: NIHMS238776
OID - NLM: PMC3020102
EDAT- 2010/12/22 06:00
MHDA- 2011/03/25 06:00
CRDT- 2010/12/22 06:00
PHST- 2010/01/31 [received]
PHST- 2010/03/15 [accepted]
AID - Recent Patents on Biotechnology 2010-4-3-4 [pii]
PST - ppublish
SO  - Recent Pat Biotechnol. 2010 Nov;4(3):189-97.