PMID- 7143431
OWN - NLM
STAT- MEDLINE
DA  - 19830107
DCOM- 19830107
LR  - 20061115
IS  - 0022-2615 (Print)
IS  - 0022-2615 (Linking)
VI  - 15
IP  - 2
DP  - 1982 May
TI  - Evidence that leptospiral lipopolysaccharide is not an important protective
      antigen.
PG  - 259-62
AB  - CBA/N mice, which could not produce antibodies against lipopolysaccharide (LPS)
      from either Escherichia coli or Leptospira interrogans serovar pomona, produced
      levels of agglutinating antibodies against leptospires similar to those produced 
      by immunologically normal CBA mice. CBA/N mice were thus resistant to acute
      leptospiral infection and CBA/N immune serum passively protected immunosuppressed
      mice from infection. The results suggest that antibodies against LPS are not
      important in protection against experimental leptospiral infection in mice.
FAU - Adler, B
AU  - Adler B
FAU - Faine, S
AU  - Faine S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - ENGLAND
TA  - J Med Microbiol
JT  - Journal of medical microbiology
JID - 0224131
RN  - 0 (Antibodies, Bacterial)
RN  - 0 (Lipopolysaccharides)
RN  - 50-18-0 (Cyclophosphamide)
SB  - IM
MH  - Animals
MH  - Antibodies, Bacterial/biosynthesis
MH  - Cyclophosphamide/pharmacology
MH  - Leptospira interrogans/*immunology
MH  - Lipopolysaccharides/*immunology
MH  - Mice
MH  - Mice, Inbred BALB C/immunology
MH  - Mice, Inbred CBA/immunology
MH  - Weil Disease/immunology
EDAT- 1982/05/01
MHDA- 1982/05/01 00:01
CRDT- 1982/05/01 00:00
PST - ppublish
SO  - J Med Microbiol. 1982 May;15(2):259-62.