PMID- 2483482
OWN - NLM
STAT- MEDLINE
DA  - 19900420
DCOM- 19900420
LR  - 20061115
IS  - 0372-9311 (Print)
IS  - 0372-9311 (Linking)
IP  - 12
DP  - 1989 Dec
TI  - [The detection of specific antigens in experimental anthrax].
PG  - 63-8
AB  - The dynamics of various specific antigens was studied in guinea pigs infected
      with strain 72/12 of Tsenkovskii's second vaccine. The study showed that at the
      acute stage of the disease toxin antigens prevailed over the levels of somatic
      antigens and nonprotective protein with a molecular weight of 79 KD. The enzyme
      immunoassay system for the detection of the lethal toxin factor permitted the
      detection of the antigen in the blood sera of 100% of infected animals at the
      prodromal period and the acute stage of the disease. In pathological material
      obtained from skin lesions the presence of toxin antigens and nonprotective
      protein was registered in 90-100% of the animals. The diagnostic significance of 
      these assays for the early rapid diagnosis of anthrax during lifetime, as well as
      for the postmortem rapid diagnosis of the disease.
FAU - Abalakin, V A
AU  - Abalakin VA
FAU - Sergeeva, L V
AU  - Sergeeva LV
FAU - Cherkasskii, B L
AU  - Cherkasskii BL
LA  - rus
PT  - English Abstract
PT  - Journal Article
TT  - Vyiavlenie spetsificheskikh antigenov pri eksperimental'noi sibirskoi iazve.
PL  - USSR
TA  - Zh Mikrobiol Epidemiol Immunobiol
JT  - Zhurnal mikrobiologii, epidemiologii, i immunobiologii
JID - 0415217
RN  - 0 (Antigens, Bacterial)
RN  - 0 (Bacterial Toxins)
RN  - 0 (Epitopes)
RN  - 0 (anthrax toxin)
SB  - IM
MH  - Animals
MH  - Anthrax/*immunology
MH  - Antigens, Bacterial/*analysis/isolation & purification
MH  - Bacillus anthracis/*immunology
MH  - Bacterial Toxins/analysis
MH  - Epitopes/*analysis/isolation & purification
MH  - Guinea Pigs
MH  - Hemagglutination Tests/methods
MH  - Immunoenzyme Techniques
MH  - Time Factors
EDAT- 1989/12/01
MHDA- 1989/12/01 00:01
CRDT- 1989/12/01 00:00
PST - ppublish
SO  - Zh Mikrobiol Epidemiol Immunobiol. 1989 Dec;(12):63-8.